stage	official_symbol	organism	pathway	function	2C	4C	8C	morula
oocyte	SMAD2	Sus scrofa	map04110	embryonic skeletal system development	0.5	0	0.11	1
oocyte	TGFB3	Homo sapiens	map04110	embryonic skeletal system development	0	0.02	0.35	1
oocyte	Tgfb3	Mus musculus	map04110	embryonic skeletal system development	0.12	0.03	0.01	0
oocyte	Tgfb2	Mus musculus	map04110	embryonic skeletal system development	0.16	0.03	0.02	0
oocyte	CDKN1C	Bos taurus	map04110	in utero embryonic development	0.08	0.37	0	0.26
oocyte	CHEK1	Bos taurus	map04110	in utero embryonic development	0.43	0.16	0.85	1
oocyte	MSH2	Bos taurus	map03430	in utero embryonic development	1	0.21	0	0.35
oocyte	SMAD4	Bos taurus	map04110	in utero embryonic development	0.41	0.07	0.1	0.74
oocyte	CCNB1	Bos taurus	map04110	in utero embryonic development	Nan	Nan	Nan	Nan
oocyte	Smad3	Mus musculus	map04110	embryonic skeletal system development	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	embryonic skeletal system development	0	0.26	0.39	0.35
oocyte	SMAD3	Sus scrofa	map04110	embryonic skeletal system development	0.49	0	0.37	0.05
oocyte	SMAD3	Homo sapiens	map04110	embryonic skeletal system development	0.37	0.54	0	0.15
oocyte	SMAD2	Homo sapiens	map04110	embryonic skeletal system development	0.8	1	0	0.11
oocyte	TGFB3	Homo sapiens	map04110	in utero embryonic development	0	0.02	0.35	1
oocyte	Tgfb3	Mus musculus	map04110	in utero embryonic development	0.12	0.03	0.01	0
oocyte	Cdkn1c	Mus musculus	map04110	in utero embryonic development	0.72	1	0.47	0
oocyte	Chek1	Mus musculus	map04110	in utero embryonic development	0.08	0.04	0.05	0
oocyte	Rpa1	Mus musculus	map03430	in utero embryonic development	0	0.06	0.17	0.25
oocyte	Msh2	Mus musculus	map03430	in utero embryonic development	0.03	0	0.33	0.71
oocyte	CCNB2	Homo sapiens	map04110	in utero embryonic development	0.79	0.67	0	0.19
oocyte	MSH2	Homo sapiens	map03430	in utero embryonic development	0.65	1	0	0.1
oocyte	CCNB1	Homo sapiens	map04110	in utero embryonic development	0.62	1	0	0.08
oocyte	Ccnb1	Mus musculus	map04110	in utero embryonic development	0.23	0.99	0.92	0
oocyte	Smad3	Mus musculus	map04110	in utero embryonic development	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	in utero embryonic development	0	0.26	0.39	0.35
oocyte	Smad4	Mus musculus	map04110	in utero embryonic development	0.34	1	0.48	0
oocyte	CDKN1C	Homo sapiens	map04110	in utero embryonic development	0.03	0.01	1	0
oocyte	Trp53	Mus musculus	map04110	in utero embryonic development	0.32	0.5	0	0.49
oocyte	SMAD3	Homo sapiens	map04110	in utero embryonic development	0.37	0.54	0	0.15
oocyte	SMAD2	Homo sapiens	map04110	in utero embryonic development	0.8	1	0	0.11
oocyte	SMAD4	Homo sapiens	map04110	in utero embryonic development	0.44	0	0.48	0.35
oocyte	Ccnb2	Mus musculus	map04110	in utero embryonic development	0	0.06	0.1	0
oocyte	SMAD2	Sus scrofa	map04110	in utero embryonic development	0.5	0	0.11	1
oocyte	CCNB2	Sus scrofa	map04110	in utero embryonic development	0.54	0.43	0.44	0
oocyte	CCNB1	Sus scrofa	map04110	in utero embryonic development	1	0.8	0.46	0.3
oocyte	CHEK1	Sus scrofa	map04110	in utero embryonic development	1	0.36	0.18	0
oocyte	SMAD3	Sus scrofa	map04110	in utero embryonic development	0.49	0	0.37	0.05
oocyte	SMAD4	Sus scrofa	map04110	in utero embryonic development	0	0.01	0.03	0.53
oocyte	TGFB1	Homo sapiens	map04110	neural tube development	Nan	Nan	Nan	Nan
oocyte	TGFB2	Homo sapiens	map04110	neural tube development	0	0.01	1	0
oocyte	Tgfb1	Mus musculus	map04110	neural tube development	Nan	Nan	Nan	Nan
oocyte	Tgfb2	Mus musculus	map04110	neural tube development	0.16	0.03	0.02	0
oocyte	ABL1	Homo sapiens	map04110	neural tube development	0.3	0.38	0.23	0
oocyte	TGFB2	Bos taurus	map04110	neural tube development	0	0	1	0.42
oocyte	TGFB1	Bos taurus	map04110	neural tube development	0	0	0	0.35
oocyte	ABL1	Bos taurus	map04110	neural tube development	0.98	1	0.09	0
oocyte	Abl1	Mus musculus	map04110	neural tube development	0.06	0	0.1	0.05
oocyte	TGFB2	Homo sapiens	map04110	pharyngeal system development	0	0.01	1	0
oocyte	Tgfb2	Mus musculus	map04110	pharyngeal system development	0.16	0.03	0.02	0
oocyte	ABL1	Sus scrofa	map04110	neural tube development	1	0.43	0.41	0
oocyte	TGFB2	Bos taurus	map04110	pharyngeal system development	0	0	1	0.42
oocyte	PRKDC	Bos taurus	map04110	somitogenesis	0.95	0.88	0.03	0
oocyte	SMAD4	Bos taurus	map04110	somitogenesis	0.41	0.07	0.1	0.74
oocyte	ATM	Bos taurus	map04110	somitogenesis	Nan	Nan	Nan	Nan
oocyte	Ep300	Mus musculus	map04110	somitogenesis	1	0.57	0.67	0
oocyte	ATM	Homo sapiens	map04110	somitogenesis	0.47	1	0.1	0
oocyte	PRKDC	Homo sapiens	map04110	somitogenesis	0.08	0.1	0.22	1
oocyte	Smad3	Mus musculus	map04110	somitogenesis	0.1	0	0.01	0.03
oocyte	Smad4	Mus musculus	map04110	somitogenesis	0.34	1	0.48	0
oocyte	Trp53	Mus musculus	map04110	somitogenesis	0.32	0.5	0	0.49
oocyte	SMAD3	Homo sapiens	map04110	somitogenesis	0.37	0.54	0	0.15
oocyte	EP300	Homo sapiens	map04110	somitogenesis	0.75	1	0.13	0
oocyte	SMAD4	Homo sapiens	map04110	somitogenesis	0.44	0	0.48	0.35
oocyte	Atm	Mus musculus	map04110	somitogenesis	0.43	0.65	1	0.99
oocyte	Prkdc	Mus musculus	map04110	somitogenesis	0.99	1	0.71	0.63
oocyte	PRKDC	Sus scrofa	map04110	somitogenesis	Nan	Nan	Nan	Nan
oocyte	Smad3	Mus musculus	map04110	heart looping	0.1	0	0.01	0.03
oocyte	SMAD3	Sus scrofa	map04110	somitogenesis	0.49	0	0.37	0.05
oocyte	SMAD3	Sus scrofa	map04110	heart looping	0.49	0	0.37	0.05
oocyte	SMAD3	Homo sapiens	map04110	heart looping	0.37	0.54	0	0.15
oocyte	SMAD4	Sus scrofa	map04110	somitogenesis	0	0.01	0.03	0.53
oocyte	EP300	Sus scrofa	map04110	somitogenesis	0	0	1	0
oocyte	HDAC1	Homo sapiens	map04110	embryonic limb morphogenesis	0.01	0	1	0.68
oocyte	HDAC1	Homo sapiens	map04110	embryonic digit morphogenesis	0.01	0	1	0.68
oocyte	TGFB2	Homo sapiens	map04110	embryonic limb morphogenesis	0	0.01	1	0
oocyte	Tgfb2	Mus musculus	map04110	embryonic limb morphogenesis	0.16	0.03	0.02	0
oocyte	Hdac2	Mus musculus	map04110	embryonic limb morphogenesis	0.04	0.33	0.64	1
oocyte	HDAC2	Homo sapiens	map04110	embryonic limb morphogenesis	0.06	0.05	1	0.74
oocyte	HDAC2	Homo sapiens	map04110	embryonic digit morphogenesis	0.06	0.05	1	0.74
oocyte	CREBBP	Homo sapiens	map04110	embryonic limb morphogenesis	0.34	1	0.45	0.9
oocyte	CREBBP	Homo sapiens	map04110	embryonic digit morphogenesis	0.34	1	0.45	0.9
oocyte	TGFB2	Bos taurus	map04110	embryonic limb morphogenesis	0	0	1	0.42
oocyte	SMAD4	Bos taurus	map04110	embryonic limb morphogenesis	0.41	0.07	0.1	0.74
oocyte	SMAD4	Bos taurus	map04110	embryonic digit morphogenesis	0.41	0.07	0.1	0.74
oocyte	Hdac1	Mus musculus	map04110	embryonic limb morphogenesis	0.32	0.65	1	0.6
oocyte	Smad4	Mus musculus	map04110	embryonic limb morphogenesis	0.34	1	0.48	0
oocyte	SMAD4	Sus scrofa	map04110	embryonic limb morphogenesis	0	0.01	0.03	0.53
oocyte	SMAD4	Homo sapiens	map04110	embryonic limb morphogenesis	0.44	0	0.48	0.35
oocyte	SMAD4	Homo sapiens	map04110	embryonic digit morphogenesis	0.44	0	0.48	0.35
oocyte	SMAD2	Sus scrofa	map04110	embryonic foregut morphogenesis	0.5	0	0.11	1
oocyte	TGFB3	Homo sapiens	map04110	embryonic neurocranium morphogenesis	0	0.02	0.35	1
oocyte	Tgfb3	Mus musculus	map04110	embryonic neurocranium morphogenesis	0.12	0.03	0.01	0
oocyte	Tgfb2	Mus musculus	map04110	embryonic neurocranium morphogenesis	0.16	0.03	0.02	0
oocyte	Hdac2	Mus musculus	map04110	embryonic digit morphogenesis	0.04	0.33	0.64	1
oocyte	ZBTB17	Bos taurus	map04110	gastrulation	0	0	0.42	0.33
oocyte	SMAD4	Bos taurus	map04110	gastrulation	0.41	0.07	0.1	0.74
oocyte	ZBTB17	Homo sapiens	map04110	gastrulation	0.36	1	0.49	0.2
oocyte	Hdac1	Mus musculus	map04110	embryonic digit morphogenesis	0.32	0.65	1	0.6
oocyte	Smad3	Mus musculus	map04110	embryonic foregut morphogenesis	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	embryonic foregut morphogenesis	0	0.26	0.39	0.35
oocyte	Smad4	Mus musculus	map04110	embryonic digit morphogenesis	0.34	1	0.48	0
oocyte	SMAD3	Sus scrofa	map04110	embryonic foregut morphogenesis	0.49	0	0.37	0.05
oocyte	SMAD3	Homo sapiens	map04110	embryonic foregut morphogenesis	0.37	0.54	0	0.15
oocyte	SMAD3	Homo sapiens	map04110	gastrulation	0.37	0.54	0	0.15
oocyte	SMAD4	Sus scrofa	map04110	embryonic digit morphogenesis	0	0.01	0.03	0.53
oocyte	SMAD2	Homo sapiens	map04110	embryonic foregut morphogenesis	0.8	1	0	0.11
oocyte	SMAD2	Homo sapiens	map04110	gastrulation	0.8	1	0	0.11
oocyte	SMAD4	Homo sapiens	map04110	gastrulation	0.44	0	0.48	0.35
oocyte	SMAD2	Sus scrofa	map04110	gastrulation	0.5	0	0.11	1
oocyte	TGFB2	Sus scrofa	map04110	gastrulation	0.03	1	0.28	0.93
oocyte	Zbtb17	Mus musculus	map04110	gastrulation	0.66	0.84	1	0.69
oocyte	Smad3	Mus musculus	map04110	gastrulation	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	gastrulation	0	0.26	0.39	0.35
oocyte	Smad4	Mus musculus	map04110	gastrulation	0.34	1	0.48	0
oocyte	SMAD3	Sus scrofa	map04110	gastrulation	0.49	0	0.37	0.05
oocyte	Trp53	Mus musculus	map04110	gastrulation	0.32	0.5	0	0.49
oocyte	SMAD4	Sus scrofa	map04110	gastrulation	0	0.01	0.03	0.53
oocyte	ZBTB17	Sus scrofa	map04110	gastrulation	0	0	0.02	0.14
oocyte	TGFB1	Homo sapiens	map04110	morphogenesis of embryonic epithelium	Nan	Nan	Nan	Nan
oocyte	TGFB2	Homo sapiens	map04110	morphogenesis of embryonic epithelium	0	0.01	1	0
oocyte	Tgfb1	Mus musculus	map04110	morphogenesis of embryonic epithelium	Nan	Nan	Nan	Nan
oocyte	Tgfb2	Mus musculus	map04110	morphogenesis of embryonic epithelium	0.16	0.03	0.02	0
oocyte	ABL1	Homo sapiens	map04110	morphogenesis of embryonic epithelium	0.3	0.38	0.23	0
oocyte	Myc	Mus musculus	map04110	middle ear morphogenesis	0.25	0.91	0.77	1
oocyte	ABL1	Sus scrofa	map04110	morphogenesis of embryonic epithelium	1	0.43	0.41	0
oocyte	TGFB2	Bos taurus	map04110	morphogenesis of embryonic epithelium	0	0	1	0.42
oocyte	TGFB1	Bos taurus	map04110	morphogenesis of embryonic epithelium	0	0	0	0.35
oocyte	ABL1	Bos taurus	map04110	morphogenesis of embryonic epithelium	0.98	1	0.09	0
oocyte	Abl1	Mus musculus	map04110	morphogenesis of embryonic epithelium	0.06	0	0.1	0.05
oocyte	Cdkn1c	Mus musculus	map04110	embryonic morphogenesis	0.72	1	0.47	0
oocyte	CDKN1C	Bos taurus	map04110	embryonic morphogenesis	0.08	0.37	0	0.26
oocyte	CDKN1C	Homo sapiens	map04110	embryonic morphogenesis	0.03	0.01	1	0
oocyte	TGFB1	Homo sapiens	map04110	embryonic liver development	Nan	Nan	Nan	Nan
oocyte	TGFB2	Homo sapiens	map04110	embryonic digestive tract development	0	0.01	1	0
oocyte	Tgfb1	Mus musculus	map04110	embryonic liver development	Nan	Nan	Nan	Nan
oocyte	Cdkn1c	Mus musculus	map04110	embryonic placenta morphogenesis	0.72	1	0.47	0
oocyte	CDKN1C	Bos taurus	map04110	embryonic placenta morphogenesis	0.08	0.37	0	0.26
oocyte	TGFB2	Sus scrofa	map04110	embryonic digestive tract development	0.03	1	0.28	0.93
oocyte	TGFB2	Bos taurus	map04110	embryonic digestive tract development	0	0	1	0.42
oocyte	TGFB1	Bos taurus	map04110	embryonic liver development	0	0	0	0.35
oocyte	CDKN1C	Homo sapiens	map04110	embryonic placenta morphogenesis	0.03	0.01	1	0
oocyte	SMAD2	Homo sapiens	map04110	embryonic organ development	0.8	1	0	0.11
oocyte	TGFB3	Homo sapiens	map04110	embryonic organ development	0	0.02	0.35	1
oocyte	Tgfb3	Mus musculus	map04110	embryonic organ development	0.12	0.03	0.01	0
oocyte	Tgfb2	Mus musculus	map04110	embryonic organ development	0.16	0.03	0.02	0
oocyte	Myc	Mus musculus	map04110	embryonic organ development	0.25	0.91	0.77	1
oocyte	Smad3	Mus musculus	map04110	embryonic organ development	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	embryonic organ development	0	0.26	0.39	0.35
oocyte	Trp53	Mus musculus	map04110	embryonic organ development	0.32	0.5	0	0.49
oocyte	SMAD3	Homo sapiens	map04110	embryonic organ development	0.37	0.54	0	0.15
oocyte	SMAD2	Sus scrofa	map04110	embryonic organ development	0.5	0	0.11	1
oocyte	SMAD3	Sus scrofa	map04110	embryonic organ development	0.49	0	0.37	0.05
oocyte	SMAD2	Sus scrofa	map04110	zygotic specification of dorsal/ventral axis	0.5	0	0.11	1
oocyte	PRKDC	Bos taurus	map04110	somite development	0.95	0.88	0.03	0
oocyte	SMAD4	Bos taurus	map04110	somite rostral/caudal axis specification	0.41	0.07	0.1	0.74
oocyte	SMAD4	Bos taurus	map04110	somite development	0.41	0.07	0.1	0.74
oocyte	ATM	Bos taurus	map04110	somite development	Nan	Nan	Nan	Nan
oocyte	Ep300	Mus musculus	map04110	somite development	1	0.57	0.67	0
oocyte	ATM	Homo sapiens	map04110	somite development	0.47	1	0.1	0
oocyte	PRKDC	Homo sapiens	map04110	somite development	0.08	0.1	0.22	1
oocyte	Smad3	Mus musculus	map04110	embryonic pattern specification	0.1	0	0.01	0.03
oocyte	Smad3	Mus musculus	map04110	somite development	0.1	0	0.01	0.03
oocyte	Smad2	Mus musculus	map04110	zygotic specification of dorsal/ventral axis	0	0.26	0.39	0.35
oocyte	Smad4	Mus musculus	map04110	somite rostral/caudal axis specification	0.34	1	0.48	0
oocyte	Smad4	Mus musculus	map04110	somite development	0.34	1	0.48	0
oocyte	SMAD3	Sus scrofa	map04110	embryonic pattern specification	0.49	0	0.37	0.05
oocyte	Trp53	Mus musculus	map04110	somite development	0.32	0.5	0	0.49
oocyte	SMAD3	Homo sapiens	map04110	embryonic pattern specification	0.37	0.54	0	0.15
oocyte	SMAD3	Homo sapiens	map04110	somite development	0.37	0.54	0	0.15
oocyte	SMAD4	Sus scrofa	map04110	somite rostral/caudal axis specification	0	0.01	0.03	0.53
oocyte	EP300	Homo sapiens	map04110	somite development	0.75	1	0.13	0
oocyte	SMAD2	Homo sapiens	map04110	zygotic specification of dorsal/ventral axis	0.8	1	0	0.11
oocyte	SMAD4	Homo sapiens	map04110	somite rostral/caudal axis specification	0.44	0	0.48	0.35
oocyte	SMAD4	Homo sapiens	map04110	somite development	0.44	0	0.48	0.35
oocyte	Atm	Mus musculus	map04110	somite development	0.43	0.65	1	0.99
oocyte	Prkdc	Mus musculus	map04110	somite development	0.99	1	0.71	0.63
oocyte	Bub1	Mus musculus	map04110	embryo development	0.6	1	0.74	0.31
oocyte	PRKDC	Sus scrofa	map04110	somite development	Nan	Nan	Nan	Nan
oocyte	SMAD3	Sus scrofa	map04110	somite development	0.49	0	0.37	0.05
oocyte	SMAD4	Sus scrofa	map04110	somite development	0	0.01	0.03	0.53
oocyte	EP300	Sus scrofa	map04110	somite development	0	0	1	0